河南农业大学学报

参考文献

[1]李琳，朱学明，鲍坚东，等.基因编辑的“前世今生”[J].浙江农业学报，2022, 34(5):1091-1102.LI L, ZHU X M, BAO J D, et al. Gene editing:past and present[J]. Acta Agriculturae Zhejiangensis,2022, 34(5):1091-1102.

[2] KIM Y G, CHA J, CHANDRASEGARAN S. Hybrid restriction enzymes:zinc finger fusions to Fok I cleavage domain[J]. Proceedings of the National Academy of Sciences of the United States of America, 1996, 93(3):1156-1160.

[3] SHUKLA V K, DOYON Y, MILLER J C, et al. Precise genome modification in the crop species Zea mays using zinc-finger nucleases[J]. Nature, 2009, 459(7245):437-441.

[4] WOOD A J, LO T W, ZEITLER B, et al. Targeted genome editing across species using ZFNs and TALENs[J]. Science, 2011, 333(6040):307.

[5] CHAR S N, UNGER-WALLACE E, FRAME B, et al.Heritable site-specific mutagenesis using TALENs in maize[J]. Plant Biotechnology Journal, 2015, 13(7):1002-1010.

[6] JINEK M, CHYLINSKI K, FONFARA I, et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity[J]. Science, 2012, 337(6096):816-821.

[7] SVITASHEV S, YOUNG J K, SCHWARTZ C, et al.Targeted mutagenesis, precise gene editing, and sitespecific gene insertion in maize using Cas9 and guide RNA[J]. Plant Physiology, 2015, 169(2):931-945.

[8]杨帆，李寅.新一代基因组编辑系统CRISPR/Cpf1[J].生物工程学报，2017, 33(3):361-371.YANG F, LI Y. The new generation tool for CRISPR genome editing:CRISPR/Cpf1[J]. Chinese Journal of Biotechnology, 2017, 33(3):361-371.

[9] ZHU H C, LI C, GAO C X. Applications of CRISPRCas in agriculture and plant biotechnology[J]. Nature Reviews Molecular Cell Biology, 2020, 21(11):661-677.

[10]黄灵芝，符晓，祁显涛，等.不同CRISPR-Cas12f系统的编辑效率比较[J].作物学报，2024, 50(10):2425-2434.HUANG L Z, FU X, QI X T, et al. Evaluation of editing efficiency of different CRISPR-Cas12f systems[J].Acta Agronomica Sinica, 2024, 50(10):2425-2434.

[11]刘相国，钱步轩，孙佳琪，等.玉米基因编辑研究进展和前景展望[J].吉林农业大学学报，2025, 47(2):191-201.LIU X G, QIAN B X, SUN J Q, et al. Research progress and prospects of maize gene editing[J]. Journal of Jilin Agricultural University, 2025, 47(2):191-201.

[12]张强，赵振宇，李平华.基因编辑技术在玉米中的研究进展[J].植物学报，2024, 59(6):978-998.ZHANG Q, ZHAO Z Y, LI P H. Research progress of gene editing technology in maize[J]. Chinese Bulletin of Botany, 2024, 59(6):978-998.

[13] KOMOR A C, KIM Y B, PACKER M S, et al. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage[J]. Nature, 2016,533(7603):420-424.

[14] CHEN K L, WANG Y P, ZHANG R, et al. CRISPR/cas genome editing and precision plant breeding in agriculture[J]. Annual Review of Plant Biology, 2019,70:667-697.

[15]周苏淮，李芳，李娟，等.植物基因组精准编辑技术：引导编辑[J].科学通报，2025, 70(16):2414-2422.ZHOU S H, LI F, LI J, et al. Plant genome precise editing technology-prime editing[J]. Chinese Science Bulletin, 2025, 70(16):2414-2422.

[16] XU W, YANG Y X, YANG B Y, et al. A design optimized prime editor with expanded scope and capability in plants[J]. Nature Plants, 2021, 8(1):45-52.

[17] SUN C, LEI Y, LI B S, et al. Precise integration of large DNA sequences in plant genomes using PrimeRoot editors[J]. Nature Biotechnology, 2023, 42(2):316-327.

[18] GAO X Q, SHIM W B, G?BEL C, et al. Disruption of a maize 9-lipoxygenase results in increased resistance to fungal pathogens and reduced levels of contamination with mycotoxin fumonisin[J]. Molecular Plant-Microbe Interactions, 2007, 20(8):922-933.

[19] LIU C L, KONG M, ZHU J J, et al. Engineering null mutants in confers resistance to ear rot caused by Fusarium verticillioides in maize[J]. Plant Biotechnology Journal, 2022, 20(11):2045-2047.

[20] SONG Y X, MA P P, GAO J Y, et al. Natural variation in maize gene ZmSBR1 confers seedling resistance to Fusarium verticillioides[J]. The Crop Journal, 2024, 12(3):836-844.

[21] CHEN C, ZHAO Y Q, TABOR G, et al. A leucine-rich repeat receptor kinase gene confers quantitative susceptibility to maize southern leaf blight[J]. New Phytologist,2023, 238(3):1182-1197.

[22] ZHU M, ZHONG T, XU L, et al. The ZmCPK39-ZmDi19-ZmPR10 immune module regulates quantitative resistance to multiple foliar diseases in maize[J].Nature Genetics, 2024, 56(12):2815-2826.

[23] LIU C L, KONG M, YANG F, et al. Targeted generation of null mutants in ZmGDIα confers resistance against maize rough dwarf disease without agronomic penalty[J]. Plant Biotechnology Journal, 2022, 20(5):803-805.

[24] XIE J P, FEI X H, YAN Q, et al. The C4 photosynthesis bifunctional enzymes, PDRPs, of maize are co-opted to cytoplasmic viral replication complexes to promote infection of a prevalent potyvirus sugarcane mosaic virus[J]. Plant Biotechnology Journal, 2024, 22(7):1812-1832.

[25] LI Y J, GU J M, MA S J, et al. Genome editing of the susceptibility gene ZmNANMT confers multiple disease resistance without agronomic penalty in maize[J]. Plant Biotechnology Journal, 2023, 21(8):1525-1527.

[26] PATHI K M, RINK P, BUDHAGATAPALLI N, et al.Engineering smut resistance in maize by site-directed mutagenesis of LIPOXYGENASE3[J]. Frontiers in Plant Science, 2020, 11:543895.

[27] LIU Y, CHEN Z Q, ZHANG C, et al. Gene editing of ZmGA20ox3 improves plant architecture and drought tolerance in maize[J]. Plant Cell Reports, 2023, 43(1):18.

[28] HABBEN J E, BAO X M, BATE N J, et al. Transgenic alteration of ethylene biosynthesis increases grain yield in maize under field drought-stress conditions[J]. Plant Biotechnology Journal, 2014, 12(6):685-693.

[29] ZHANG J, FENGLER K A, VAN HEMERT J L, et al.Identification and characterization of a novel stay-green QTL that increases yield in maize[J]. Plant Biotechnology Journal, 2019, 17(12):2272-2285.

[30] ZHANG H L, YU F F, XIE P, et al. A Gγ protein regulates alkaline sensitivity in crops[J]. Science, 2023,379(6638):eade8416.

[31]吕庆雪，汤继超，周德龙，等.利用CRISPR-Cas9技术编辑ZmSh2基因创制超甜玉米新种质[J].玉米科学，2024, 32(3):62-66.LüQ X, TANG J C, ZHOU D L, et al. Using CRISPRCas9 technique to edit ZmSh2 gene to create new germplasm of super sweet maize[J]. Journal of Maize Sciences, 2024, 32(3):62-66.

[32] DONG L, QI X T, ZHU J J, et al. Supersweet and waxy:meeting the diverse demands for specialty maize by genome editing[J]. Plant Biotechnology Journal,2019, 17(10):1853-1855.

[33] GAO H R, GADLAGE M J, LAFITTE H R, et al.Superior field performance of waxy corn engineered using CRISPR-Cas9[J]. Nature Biotechnology, 2020,38(5):579-581.

[34] MA M Z, SUN S Q, ZHU J J, et al. Engineering high amylose and resistant starch in maize by CRISPR/Cas9-mediated editing of starch branching enzymes[J]. The Crop Journal, 2024, 12(4):1252-1258.

[35] YU Y H, LI W Q, LIU Y F, et al. A Zea genusspecific micropeptide controls kernel dehydration in maize[J]. Cell, 2025, 188(1):44-59.

[36] WANG H H, HUANG Y C, LI Y J, et al. An ARF gene mutation creates flint kernel architecture in dent maize[J]. Nature Communications, 2024, 15:2565.

[37] HURST J P, SATO S, FERRIS T, et al. Editing the 19kDa alpha-zein gene family generates non-opaque2-based quality protein maize[J]. Plant Biotechnology Journal, 2024, 22(4):946-959.

[38] WANG Y X, LIU X Q, ZHENG X X, et al. Creation of aromatic maize by CRISPR/cas[J]. Journal of Integrative Plant Biology, 2021, 63(9):1664-1670.

[39]张翔，史亚兴，卢柏山，等.利用CRISPR/Cas9技术编辑BADH2-1/BADH2-2创制香米味道玉米新种质[J].中国农业科学，2021, 54(10):2064-2075.ZHANG X, SHI Y X, LU B S, et al. Creation of new maize variety with fragrant rice like flavor by editing BADH2-1 and BADH2-2 using CRISPR/Cas9[J]. Scientia Agricultura Sinica, 2021, 54(10):2064-2075.

[40] XIONG W D, WU Z Y, LIU Y C, et al. Mutation of 4-coumarate:coenzyme a ligase 1 gene affects lignin biosynthesis and increases the cell wall digestibility in maize brown midrib5 mutants[J]. Biotechnology for Biofuels, 2019, 12:82.

[41] CHEN W K, CHEN L, ZHANG X, et al. Convergent selection of a WD40 protein that enhances grain yield in maize and rice[J]. Science, 2022, 375(6587):7985.

[42] LIU L, GALLAGHER J, AREVALO E D, et al.Enhancing grain-yield-related traits by CRISPR-Cas9promoter editing of maize CLE genes[J]. Nature Plants, 2021, 7(3):287-294.

[43] ZHANG L, FU M M, LI W Y, et al. Genetic variation in ZmKW1 contributes to kernel weight and size in dent corn and popcorn[J]. Plant Biotechnology Journal,2024, 22(6):1453-1467.

[44] GUO T, JIANG L G, LI B, et al. Confers quantitative variation in pollen number and boosts hybrid seed production in maize[J]. Plant Biotechnology Journal,2023, 21(10):1978-1989.

[45] ZHAO B B, XIA Z C, SUN C H, et al. CRISPR/Cas9-mediated genomic editing of Brachytic2 creates semidwarf mutant alleles for tailored maize breeding[J].Plant Biotechnology Journal, 2025, 23(4):1133-1135.

[46]张文婷，王煜，赵丫杰，等. ZmCYP72A5基因调节玉米株高和抽穗时间的研究[J].山东农业大学学报（自然科学版），2023, 54(1):1-8.ZHANG W T, WANG Y, ZHAO Y J, et al. Study of ZmCYP72A5 gene on regulating plant height and heading time in maize[J]. Journal of Shandong Agricultural University(Natural Science Edition), 2023, 54(1):1-8.

[47]石佳鑫，刘凯，朱金洁，等.基因编辑技术改良玉米株型增加杂交种产量[J].生物技术通报，2023, 39(8):62-69.SHI J X, LIU K, ZHU J J, et al. Gene editing reshaping maize plant type for increasing hybrid yield[J]. Biotechnology Bulletin, 2023, 39(8):62-69.

[48] TIAN J G, WANG C L, CHEN F Y, et al. Maize smartcanopy architecture enhances yield at high densities[J]. Nature, 2024, 632(8025):576-584.

[49] SHENG H J, ZHANG H, DENG H, et al. Maize COMPACT PLANT 3 regulates plant architecture and facilitates high-density planting[J]. The Plant Cell,2025, 37(2):29.

[50] SIMMONS C R, LAFITTE H R, REIMANN K S, et al.Successes and insights of an industry biotech program to enhance maize agronomic traits[J]. Plant Science,2021, 307:110899.

[51] GATICA-ARIAS A. The regulatory current status of plant breeding technologies in some Latin American and the Caribbean countries[J]. Plant Cell, Tissue and Organ Culture, 2020, 141(2):229-242.

[52] TSUDA M, WATANABE K N, OHSAWA R. Regulatory status of genome-edited organisms under the Japanese Cartagena act[J]. Frontiers in Bioengineering and Biotechnology, 2019, 7:387.

[53] LIANG Z, CHEN K L, LI T D, et al. Efficient DNAfree genome editing of bread wheat using CRISPR/Cas9ribonucleoprotein complexes[J]. Nature Communications, 2017, 8:14261.

[54]国家农业转基因生物安全委员会. 2024年农业基因编辑生物安全证书（生产应用）批准清单[J].中国种业，2024(6):207.National Biosafety Committee of Agricultural Genetically Modified Organisms. Approved list of biosafety certificate(production application)for agricultural gene editing in 2024[J]. China Seed Industry, 2024(6):207.

[55] QIU F T, XUE C X, LIU J X, et al. An efficient mRNA delivery system for genome editing in plants[J].Plant Biotechnology Journal, 2025, 23(4):1348-1358.

[56] HU J C, LI S Y, LI Z L, et al. A barley stripe mosaic virus-based guide RNA delivery system for targeted mutagenesis in wheat and maize[J]. Molecular Plant Pathology, 2019, 20(10):1463-1474.

[57] KELLIHER T, STARR D, SU X J, et al. One-step genome editing of elite crop germplasm during haploid induction[J]. Nature Biotechnology, 2019, 37(3):287-292.

[58] WANG B B, ZHU L, ZHAO B B, et al. Development of a haploid-inducer mediated genome editing system for accelerating maize breeding[J]. Molecular Plant,2019, 12(4):597-602.

[59] CLAEYS H, NEYRINCK E, DUMOULIN L, et al.Coordinated gene upregulation in maize through CRISPR/Cas-mediated enhancer insertion[J]. Plant Biotechnology Journal, 2024, 22(1):16-18.

[60] ZHANG Y, XIAN Y B, YANG H, et al. A novel geminivirus-derived 3'flanking sequence of Terminator mediates the gene expression enhancement[J]. Plant Biotechnology Journal, 2025, 23(4):1053-1066.

[61] LOU H C, LI S J, SHI Z H, et al. Engineering sourcesink relations by prime editing confers heat-stress resilience in tomato and rice[J]. Cell, 2025, 188(2):530-549.